Risk Factors for Proliferative Sickle Retinopathy
نویسندگان
چکیده
منابع مشابه
Angiogenic factors in human proliferative sickle cell retinopathy.
BACKGROUND/AIMS Preretinal neovascular formations called sea fans develop at the border of non-perfused peripheral retina in sickle cell retinopathy. Angiogenic factors which could contribute to their development, however, have not been examined previously. The objective of this study was to determine immunohistochemically if vascular endothelial growth factor (VEGF) or basic fibroblast growth ...
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RESULTS. The baseline characteristics identified as risk factors for high-risk PDR were increased severity of retinopathy, decreased visual acuity (or increased extent of macular edema), higher glycosylated hemoglobin, history of diabetic neuropathy, lower hematocrit, elevated triglycerides, lower serum albumin, and, in persons with mild to moderate nonproliferative retinopathy, younger age (or...
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Complete closure of retinal neovascularisation due to proliferative sickle cell retinopathy was achieved in 28 'sea fans' (areas of neovascularisation) in 9 eyes of 9 patients by means of a triple freeze-thaw technique. However, 2 eyes developed subsequent rhegmatogenous retinal detachments, presumably related to vitreous traction on necrotic retina. We therefore recommend photocoagulation as...
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Haematological indices were investigated in 261 patients with homozygous sickle cell disease, 29 of whom had developed proliferative sickle retinopathy (PSR). After allowing for age-related effects, male patients with high Hb (> 9 g/dl) and low HbF (< 5%) levels appeared to constitute a high risk group for PSR. This relationship was not evident in females, PSR being observed in patients with lo...
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ژورنال
عنوان ژورنال: Retina
سال: 1990
ISSN: 0275-004X
DOI: 10.1097/00006982-199010000-00018